Which clause in Article 6 establishes the Constitution as the supreme law of the land?

The Supremacy Clause is a crucial component of Article 6 of the United States Constitution. It establishes that the Constitution, along with federal laws made pursuant to it and treaties made under its authority, takes precedence over state laws and constitutions. This means that when there is a conflict between federal and state law, federal law prevails, ensuring a uniform legal framework throughout the nation. This clause highlights the federal system of government and reinforces the authority of the Constitution as the highest form of law in the United States. In essence, it affirms the fundamental principle that states cannot make laws that supersede federal legislation, thereby maintaining the legal hierarchy established by the Constitution.